Type 5 Diabetes is (finally) Real

May the real Beta-cell please stand up

A few months ago, we discussed the South asian beta cell as a Fragile Engine: this thesis that South Asian beta cells are 4-cylinder motors, not V8s. Smaller islets, lower reserve, lower capacity. Data from India showed a 45% reduction in the proportion of large islets compared to American samples. We start with less, and what we have burns out faster.

I…